interleukin-10

[Nature] The authors identified the metabolite and neurotransmitter GABA as a candidate signaling molecule synthesized and secreted by activated B cells and plasma cells.

[Science Translational Medicine] Investigators examined the intersection of maternal-fetal antibody transfer, viral-induced placental interferon responses, and fetal sex in pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

[Blood Cancer Journal] The authors found that interleukin-10 receptor (IL-10R) was overexpressed in most acute myeloid luekemia cells, and played an important role in promoting the stemness of leukemia cells.

[British Journal of Cancer] Researchers discuss the immunostimulatory and immunosuppressive roles of interleukin-10 (IL-10) in the glioblastoma tumour microenvironment while considering IL-10-targeted treatment strategies.

[Circulation Research] The authors tested whether silencing netrin-1 in advanced atherosclerosis could resolve arterial inflammation and regress plaques.

[Scientific Reports] Scientists demonstrated that membrane vesicles from Lacticaseibacillus rhamnosus JB-1 were endocytosed in a likely clathrin-dependent manner by both mouse and human intestinal epithelial cells (IECs) in vitro and by mouse IEC in vivo.