Tag results:
intestinal epithelial cells
Intestinal Cell News
GOLM1 Restricts Colitis and Colon Tumorigenesis by Ensuring Notch Signaling Equilibrium in Intestinal Homeostasis
[Signal Transduction and Targeted Therapy] Scientists found that that Golgi membrane protein 1 (GOLM1) suppressed colorectal tumorigenesis via maintenance of intestinal epithelial barrier.
Organoid News
Interleukin-37 Regulates Innate Immune Signaling in Human and Mouse Colonic Organoids
[Scientific Reports] Scientists characterized innate immune responses of human and murine colonoids to bacteria and host products and the role of IL-37/SIGIRR in regulating these responses.
Intestinal Cell News
Efferocytosis by Paneth Cells within the Intestine
[Current Biology] Through a series of studies spanning in vitro efferocytosis, ex vivo intestinal organoids, and in vivo Cre-mediated deletion of Paneth cells, researchers showed that Paneth cells mediate apoptotic cell uptake of dying neighbors.
Intestinal Cell News
Bacterial Detection by NAIP/NLRC4 Elicits Prompt Contractions of Intestinal Epithelial Cell Layers
[Proceedings of the National Academy of Sciences of the United States of America] Researchers showed that untransformed intestinal epithelial cell layers initiate immediate focal contractions, affecting hundreds to thousands of epithelial cells, in response to bacterial infection.
Intestinal Cell News
Epithelial Sensing of Microbiota-Derived Signals
[Genes & Immunity] The authors highlight the pathways by which intestinal epithelial cells sense microbiota-derived signals and the necessity of these detection pathways in maintaining epithelial barrier integrity.
Dermal Cell News
Exopolysaccharide from Lactobacillus plantarum HY7714 Protects against Skin Aging through Skin-Gut Axis Communication
[Molecules] Scientists studied the role of exopolysaccharides produced by lactic acid bacteria identified as Lactobacillus plantarum HY7714 in regulating tight junctions in intestinal epithelial cells and increasing moisture retention in human dermal fibroblasts cells.