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intestinal epithelial cells

Restitution of Epithelial Cells during Intestinal Mucosal Wound Healing: The Effect of a Polysaccharide from the Sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden

[Journal of Ethnopharmacology] Researchers investigated the effect and mechanism of β-glucan prepared from Lignosus rhinocerotis using an enzymatic method on epithelial restitution during intestinal mucosal damage.

Differential Protection by Anthocyanin-Rich Bilberry Extract and Resveratrol against Lipid Micelle-Induced Oxidative Stress and Monolayer Permeability in Caco-2 Intestinal Epithelial Cells

[Food & Function] In a Caco-2 cell model of dietary fat-induced intestinal epithelial cell cytotoxicity, oxidative stress and barrier impairment, researchers investigated the relative protection afforded by an anthocyanin-rich bilberry extract or resveratrol.

Signaling Pathways in Intestinal Homeostasis and Colorectal Cancer: KRAS at Centre Stage

[Cell Communication and Signaling] Scientists summarize the signaling pathways contributing to intestinal cell fates and homeostasis functions, focusing on intestinal stem cell proliferation, cell junction formation, remodeling, hypoxia, the impact of intestinal microbiota, the immune system, inflammation, and metabolism.

Plectin Ensures Intestinal Epithelial Integrity and Protects Colon against Colitis

[Mucosal Immunology] Mechanistically, plectin deficiency in intestinal epithelial cell led to aberrant keratin filament network organization and the formation of dysfunctional hemidesmosomes and intercellular junctions.

MALAT1 Maintains the Intestinal Mucosal Homeostasis in Crohn’s Disease via the miR-146b-5p-CLDN11/NUMB Pathway

[Journal of Crohns & Colitis] Effects of intestinal epithelial cells transfected with metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) lentiviruses and Smart Silencer, on monolayer permeability and apical junction complex proteins were analyzed.

Effect of Roasted Peanut Allergen Ara H 3 Protein on the Sensitization of Caco-2 Cells

[Journal of the Science of Food and Agriculture] To evaluate the sensitization mechanism of peanut allergen Ara h 3, Caco‐2 cells as the model, which has the similar structure and function to differentiated small intestinal epithelial cells.

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