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irritable bowel syndrome

Role of Bile Acids and Their Receptors in Gastrointestinal and Hepatic Pathophysiology

[Nature Reviews Gastroenterology & Hepatology] The authors provide a summary of the role of bile acids (BAs) and their disrupted homeostasis in the development of gastrointestinal and hepatic disorders and present novel insights on how targeting BA pathways might contribute to novel treatment strategies for these disorders.

Biomerica Receives Notice of Allowance from Canadian Patent Office for Patent Covering Irritable Bowel Syndrome (IBS) Food Sensitivity Testing & Treatment

[Biomerica, Inc. (GlobeNewswire, Inc.)] Biomerica, Inc. announced that the Canadian Patent Office has issued a notice of allowance for Biomerica’s patent application pertaining to the company’s InFoods® diagnostic guided therapy platform technology that offers a novel approach in the treatment of patients suffering from IBS.

Endotrophin and C6Ma3, Serological Biomarkers of Type VI Collagen Remodeling, Reflect Endoscopic and Clinical Disease Activity in IBD

[Scientific Reports] Scientists investigated if remodeling of the intestinal basement membrane type VI collagen was associated with pathophysiological changes in Crohn’s disease and ulcerative colitis.

Knight Therapeutics Announces Canadian Commercial Launch of IBSRELA™ – New Innovative Treatment for Irritable Bowel Syndrome with Constipation

[Knight Therapeutics Inc.] Knight Therapeutics, Inc. announced the Canadian commercial availability of IBSRELA, a first-in-class therapy for the treatment of IBS with constipation in adults.

Local Immune Response to Food Antigens Drives Meal-Induced Abdominal Pain

[Nature] Scientists showed that a bacterial infection and bacterial toxins could trigger an immune response that led to the production of dietary-antigen-specific IgE antibodies in mice, which were limited to the intestine.

FDA Authorizes New IND to Evaluate Impact of Multi-Strain Probiotic DS-01TMon Gut Microbiota of Patients with IBS

[Seed Health Inc. (PRNews] The regulatory acceptance enables a team of gastroenterologists at Beth Israel Deaconess Medical Center to initiate a Phase II randomized, triple-blind, and placebo-controlled clinical trial to investigate the role of the gut microbiome in patients with Irritable Bowel Syndrome, as well as the impact of DS-01™ on both intestinal cells and metabolic output of the native intestinal microbial communities.

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