ischemic stroke

[Translational Stroke Research] The authors provide a futher understanding of the therapeutic role of neural stem cells for ischemic stroke, and evaluate their prospects for future application in clinical patients of ischemic stroke.

[Signal Transduction and Targeted Therapy] To screen the potential biomarkers of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), proteomic analysis was performed to identify those distinct plasma protein profiles in AIS due to LVO with different collateral status.

[Cell Death Discovery] The co-culture of endothelial cells with CRTC1-deficient neurons aggravated the cell vulnerability to hypoxia, also supporting the idea that miRNA-132/212 cluster was regulated by CRTC1 and acted as a crucial role in the mitigation of ischemic damage.

[Stem Cells Translational Medicine] Dr. Sara Palma-Tortosa is the 2021 recipient of the STEM CELLS Translational Medicine (SCTM) Young Investigator Award. The award honors a young researcher who served as the principal author of an article published in SCTM that, over the course of a year, is deemed to have the most impact.

[Nature Communications] Utilizing single-nuclei transcriptomics to characterize astrocytes after ischemic stroke in the visual cortex of the marmoset monkey, researchers observed nearly complete segregation between stroke and control astrocyte clusters.

[Stem Cells International] Mesenchymal stem cell (MSC) transplantation therapy, which can trigger neuronal regeneration and repair, has been considered as a significant advance in treatment of ischemic stroke.