The authors demonstrated that Pannexin 3 (Panx3) regulated skin development by modulating the transcription factor, Epiprofin (Epfn). In cell culture, Panx3 overexpression promoted HaCaT cell differentiation, cell cycle exit and enhanced Epfn expression.
[Scientific Reports]
Zhang, P., Ishikawa, M., Doyle, A., Nakamura, T., He, B., & Yamada, Y. (2021). Pannexin 3 regulates skin development via Epiprofin. Scientific Reports, 11(1), 1779. https://doi.org/10.1038/s41598-021-81074-1 Cite
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