keratinocytes

[Science Translational Medicine] Scientists performed single-cell RNA sequencing on affected and unaffected skin from patients with vitiligo, as well as healthy controls, to define the role of each cell type in coordinating autoimmunity during disease progression.

[Scientific Reports] Scientists examined if blocking aquaporin 3 could interfere arsenic-induced autophagy in keratinocytes. Expression of aquaporin 3 was increased in arsenical cancers and in arsenic-treated keratinocytes.

[Journal of Investigative Dermatology] The expression of three-hydroxy-3-methylglutaryl coenzyme A synthase 1 in cultured keratinocytes was up-regulated by exogenous Gal-7 and down-regulated in Gal-7 siRNA transfected cells.

[International Journal of Dermatology] Dermal mesenchymal stem cells were cocultured with primary keratinocytes either from psoriatic lesions or from normal subjects using Transwell plate. Expression levels of proteins were analyzed by Western blotting.

[Scientific Reports] Keratinocytes derived from hypertrophic scar tissue were cultured and expression of proliferation markers, activation markers, differentiation markers, apoptosis factors, and proliferation/differentiation regulators was investigated to compared with that of those in keratinocytes derived from normal skin tissue.

[International Journal of Biological Macromolecules] Researchers presented alginate, gelatin and diethylaminoethyl cellulose based bioink formulation and its application in bioprinting and biofabrication of skin tissue equivalents.