keratinocytes

[Scientific Reports] Scientists showed that patients with psoriasis had increased levels of matrix metalloproteinase13 protein in skin lesions and serum samples.

[Nature Immunology] Scientists investigated the single-cell phenotypes associated with antimicrobial responses in human leprosy granulomas by applying single-cell and spatial sequencing to leprosy biopsy specimens.

[Cell] Researchers showed that the skin microbiota promotes the discrete expression of defined endogenous retroviruses.

[Communications Biology] Scientists demonstrated that both diabetic foot ulcers and venous leg ulcers exhibited global deregulation of cytoskeletal organization in genomic comparison to normal skin and acute wounds.

[Scientific Reports] Investigators characterized the antimicrobial effects of PLNC8 αβ on cell signaling pathways and inflammatory responses of human keratinocytes infected with S. aureus.

[NPJ Regenerative Medicine] Scientists summarize the use of different human cell populations for preclinical and clinical tissue-engineered skin substitutes under research, remarking their strengths and limitations and discuss the future perspectives, which could be useful for wound healing purposes.