leukemia

[Leukemia] Researchers investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

[Leukemia] Scientists investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

[Cancer Discovery] Scientists generated ex vivo drug response and multi-omics profiling data for a prospective series of 252 samples from 186 acute myeloid leukemia patients. Functional precision medicine tumor board integrated clinical, molecular and functional data for application in clinical treatment decisions.

[Scientific Reports] Researchers evaluated the usefulness of plasma concentration of circulating mir-146a as a non-invasive biomarker for acute lymphoblastic leukemia. Total RNA including miRNA was isolated from 110 plasma samples of patients, healthy controls and follow up cases and reverse transcribed.

[Cancer Science] The authors investigated the anti-adult T cell leukemia/lymphoma effects of a novel oral HSP90 inhibitor TAS-116 and the mechanisms involved in ex vivo and in vivo preclinical models.

[Molecular Cancer Research] Researchers revealed the breadth of SWI/SNF dependency in leukemia and supported targeting SWI/SNF catalytic function as a potential therapeutic strategy in acute myeloid leukemia.