leukocytes

[Frontiers in Immunology] According to large-scale single-cell analysis, recovered patients, who had severe symptoms, still exhibited peripheral immune disorders one-two months after symptom onset.

[Stem Cell Research] The authors generated a Beta2-microglobulin (B2M) homozygous knockout somatic cell nuclear transfer-induced ESC line using CRISPR/Cas9-mediated gene targeting.

[International Journal of Biological Sciences] Efforts have been made to generate immune-escaping human embryonic stem cells where T cell immunity was evaded by defecting β-2-microglobulin, a common unit for human leukocyte antigen class I, and NK cells were inhibited via ectopic expression of HLA-E or -G.

[Scientific Reports] Scientists found that cytokine-specific autoantibodies (c-aAb) levels were stable over the course of hematopoietic stem cell transplantation, including at high titres, with few individuals seeming to acquire high-titre levels of c-aAbs.

[Acta Pharmacologica Sinica] Scientists demonstrated that GPR84 was highly upregulated in inflamed colon tissues of active ulcerative colitis patients and dextran sulfate sodium-induced colitis mice.

[Pediatric Research] In a systematic review, scientists evaluated the efficacy and the possible application of a new diagnostic method in febrile children, along with challenges in its implementation.