Tag results:
liquid chromatography
Pancreatic Cell News
Rhoifolin from Plumula Nelumbinis Exhibits Anti-cancer Effects in Pancreatic Cancer via AKT/JNK Signaling Pathways
[Scientific Reports] Cell viability assay revealed that apiin, rhoifolin, and vitexin could inhibit proliferation of PANC-1 and ASPC-1, with rhoifolin showing the maximum inhibitory effect.
Dermal Cell News
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics
[Frontiers in Oncology] Investigators revealed that PLA2G6 was up-regulated in cutaneous malignant melanoma tissues compared to nevus tissues, as well as increased in vitro in SK-MEL-28 and M14 melanoma cell lines compared to human melanocytes.
Hematopoiesis News
Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation
[Journal of Proteome Research] The authors performed an in-depth glycosphingolipid (GSL) glycan analysis of 19 AML cell lines using porous graphitized carbon liquid chromatography-mass spectrometry revealing strikingly different GSL glycan profiles between the various AML cell lines.
Mesenchymal Cell News
Characterizing Human Mesenchymal Stromal Cells’ Immune-Modulatory Potency Using Targeted Lipidomic Profiling of Sphingolipids
[Cytotherapy] The authors characterized MSCs derived from bone marrow, adipose tissue and umbilical cord tissue for sphingolipids, a class of bioactive lipids, using liquid chromatography/tandem mass spectrometry.
ESC & iPSC News
Histone Variant macroH2A1.1 Enhances Non-homologous End Joining-Dependent DNA Double-Strand-Break Repair and Reprogramming Efficiency of Human iPSCs
[Stem Cells] Researchers evaluated the splicing isoforms of histone variant macroH2A1, macroH2A1.1 and macroH2A1.2, as potential regulators of DNA damage repair during iPSC reprogramming.
Prostate Cell News
Comparative Proteome Analysis Identified CD44 as a Possible Serum Marker for Docetaxel Resistance in Castration-Resistant Prostate Cancer
[Journal of Cellular and Molecular Medicine] High serum CD44 levels may help identify docetaxel-resistant patients and may thereby help optimize clinical decision-making regarding type and timing of therapy for metastatic CRPC patients patients.