liquid chromatography

[Metabolomics] Researchers combined determination of bile acids and molecular lipids by liquid chromatography with ultra-high-resolution mass spectrometry, and separately quantified cord blood concentrations of sixteen poly-/per-fluoroalkyl substances in a cohort of Chinese infants in a cross-sectional study.

[Cell Death & Disease] Scientists characterized the gastric microbiome and metabolome profiles of 37 gastric cancer tumor tissues and matched non-tumor tissues using 16s rRNA gene sequencing and ultrahigh performance liquid chromatography tandem mass spectrometry, respectively.

[Scientific Reports] Providing a 3D permissive environment with epothilone B significantly improved motor neuron-like cell differentiation and maturation of human endometrial stem cells (hEnSCs) and was a promising approach to replace lost neurons after spinal cord injury.

[Journal of Ethnopharmacology] Scientists reported that Anemarrhenae Rhizoma flavonoids inhibited benign prostatic hyperplasia-related inflammation in vivo and in vitro by targeting arachidonic acid metabolism and interfering with cyclooxygenase (COX) and lipoxygenase (LOX) pathways.

[Cytotherapy] The authors provided a platform for identifying markers for predicting MSC functional capacity using partial least squares regression modeling that could be used as release criteria and guide future manufacturing strategies for mesenchymal stromal cells and other cell therapies.

[Archiv Der Pharmazie] Investigators explored the mechanisms of action of alsevirone in prostate cancer in vitro and in vivo: CYP17A1 inhibition, cytotoxic, apoptotic, and antitumor effects compared with abiraterone.