liver fibrosis

[Cell Death & Disease] Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.

[Liver International] The authors used a monoclonal antibody targeting the C-telopeptide of type III collagen following C-proteinase cleavage to develop and validate a neo-epitope-specific enzyme-linked immunosorbent assay.

[Cell Death & Disease] Researchers investigated the functional subsets of γδ T cells in hepatic fibrosis and to further explore the underlying causes and drivers of migration.

[Cell Death Discovery] Scientists found that specific deletion of Cbl-b and c-Cbl in CD11c+ cells, predominantly in dendritic cells (DCs), led to liver fibrosis, cirrhosis, and accumulation of systemic conventional Type I DCs due to enhanced cell proliferation and decreased cell apoptosis.

[Nature Communications] Scientists reported a targeted antifibrotic peptide-delivery system in which fibroblast activation protein, which was overexpressed in fibrotic regions of the liver, liberated the antifibrotic peptide melittin by cleaving a fibroblast activation protein-specific site in the peptide.

[Experimental and Molecular Medicine] Researchers investigated the role of hepatic Sestrin2 in cholestatic liver injury and its underlying mechanisms using in vivo and in vitro approaches.