lung cancer cells

[Scientific Reports] Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.

[Bioengineered] Scientists suggested that circ-UBE2D2 promoted the proliferation, migration and invasion but restrained apoptosis of lung cancer cells by regulating miR-376a-3p/eukaryotic translation initiation factor 4γ2 axis.

[Scientific Reports] The authors carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which was induced both in lung adenocarcinoma and lung squamous cell carcinoma.

[Archiv Der Pharmazie] Scientists provided novel androgen receptor (AR)-directed proteolysis-targeting chimeras (PROTACs) and a clear rationale for further investigating AR involvement in lung cancer models.

[Oncotarget] The researchers' analysis of The Cancer Genome Atlas (TCGA) expression data revealed that p50-associated COX-2 extragenic RNA (PACER) expression was significantly higher in lung adenocarcinomas than normal lung tissues.

[Cell Death & Disease] Investigators demonstrated the role of oncogenic Ras/syntenin-1 axis in the release of small extracellular vesicles (sEVs) and elucidated the function of syntenin-1-mediated miRNAs in sEVs in lung cancer progression.