lung cancer

[Thoracic Cancer] Scientists identified radio-responsive genes and explored the biological function of encoded proteins in NSCLC.

[Acta Pharmacologica Sinica] Investigators demonstrated that mitogen-activated protein (MAP) kinase kinase kinase 9 (MAP3K9) was the target of miR-148a-3p and that MAP3K9 levels were significantly increased in both lung adenocarcinoma cell lines and clinical tumor tissues.

[Journal of Cellular and Molecular Medicine] Scientists found that A549 human lung cancer cells stably expressing vestigial-like family member 3 exhibited spindle-like morphological changes, reduction in the epithelial marker E-cadherin and induction of the mesenchymal marker Snail.

[Supportive Care in Cancer] Scientists suggest that physical activity is low among surgical lung cancer patients, and it may not recover within 3 months following surgery and that physical activity has the potential to improve postoperative outcomes.

[Oncogene] The authors evidenced that cholesterol promoted cell proliferation and invasion of lung adenocarcinoma (LAC) in vitro as well as LAC metastasis in vivo.

[Cell Death Discovery] Using iTRAQ-based quantitative proteomics analysis, we identified that nicotinamide N-methyltransferase was significantly increased in epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-resistant NSCLC cells.