Tag results:
lymphocytes
Human Immunology News
Diversity of Human NK Cell Developmental Pathways Defined by Single-Cell Analyses
[Current Opinion in Immunology] Investigators offer a brief review of new insights into human NK cell diversity specifically defined by next generation sequencing and single-cell transcriptomic studies.
Human Immunology News
Single-Cell Transcriptomic Identified HIF1A as a Target for Attenuating Acute Rejection after Heart Transplantation
[Basic Research in Cardiology] A Total of 20 immune cell subtypes were identified among 46,040 cells. The function of immune cells in acute rejection were illustrated simultaneously.
Immunology of Infectious Disease News
Genetic Mapping Reveals Nfkbid as a Central Regulator of Humoral Immunity to Toxoplasma gondii
[PLoS Pathogens] The authors reported that unlike susceptible C57BL/6J mice, A/J mice were highly resistant to secondary infection.
Immunology of Infectious Disease News
Robust Immune Responses Are Observed after One Dose of BNT162b2 mRNA Vaccine Dose in SARS-CoV-2 Experienced Individuals
[Science Translational Medicine] Scientists evaluated longitudinal immune responses to two-dose BNT162b2 mRNA vaccination in 15 adults who had experienced COVID-19, compared to 21 adults who did not have prior COVID-19.
Immune Regulation News
TNF Plays a Crucial Role in Inflammation by Signaling via T Cell TNFR2
[Proceedings of the National Academy of Sciences of the United States of America] Exposure of mouse CD4+ T cells to TNF and TGF-β generated Th17 cells that expressed low levels of IL-17 and high levels of inflammatory markers independently of IL-6 and STAT3.
Hematopoiesis News
Molecular Partners Announces Research Collaboration with University of Bern to Develop MP0533, a Multispecific DARPin for the Treatment of AML
[Molecular Partners AG] Molecular Partners AG announced a research collaboration with University of Bern, to advance the development of the company’s wholly owned acute myeloid leukemia candidate, MP0533, into the clinic.