lymphoid cells

[Nature Immunology] Researchers identified that targeting the epigenetic modifier BMI-1 in mice improved humoral responses to chronic lymphocytic choriomeningitis virus.

[Mucosal Immunology] Scientists summarize current knowledge regarding mucosal Tregs in both health and disease.

[Cell Reports] Researchers showed that the single-cell landscape of peripheral immune responses is reprogrammed in thrombocytopenia syndrome (SFTS) and characterized by monocyte shift to an intermediate type along with complement activation, perturbation of plasmablast composition, and highly exhausted T cells.

[Molecular Therapy-Oncolytics] A novel DNA vaccine containing dual antigens of fibrinogen-like protein 1 and carbonic anhydrase IX was developed and intramuscularly delivered by PLGA/PEI nanoparticles for renal cancer therapy.

[eLife] The authors characterized cell free DNA released from specific immune cell types in healthy individuals, cross sectionally and longitudinally.

[Molecular Therapy-Oncolytics] Investigators combinated an oncolytic adenovirus carrying Decorin with a CAR-T targeting carbonic anhydrase IX to perform the anti-tumor activity for renal cancer cells.