Tag results:

lymphoid cells

Intracolonic Neuropeptide Y Y1 Receptor Inhibition Attenuates Intestinal Inflammation in Murine Colitis and Cytokine Release in IBD Biopsies

[Inflammatory Bowel Diseases] Researchers investigated if selective blocking of neuropeptide Y (NPY) receptors, NPY1R or NPY2R, using small molecule non-peptide antagonists (BIBP-3222 for NPY1R and BIIE-0246 for NPY2R) in the colon could attenuate intestinal inflammation by lowering TNF levels.

CAR-T Cell Therapy in T Cell Malignancies: Is Success a Low-Hanging Fruit?

[Stem Cell Research & Therapy] Investigators highlight the preclinical and clinical efforts made for addressing the drawbacks and also review additional potent stratagems that could improve CAR-T therapy in T cell malignancies.

Intrauterine Administration of Peripheral Blood Mononuclear Cells (PBMCs) Improves Embryo Implantation in Mice by Regulating Local Treg/Th17 Cell Balance

[Journal of Reproduction and Development] Investigators determined the effect of intrauterine administration of mouse PBMCs prior to embryo implantation on endometrial receptivity and embryo implantation, and examined the underlying mechanism of Treg/Th17 cell balance following intrauterine administration of PBMCs.

Biomaterial-Enabled Induction of Pancreatic-Specific Regulatory T Cells through Distinct Signal Transduction Pathways

[Drug Delivery and Translational Research] Scientists used poly (lactic-co-glycolide) to co-encapsulate type 1 diabetes-relevant antigen and 3 distinct TREG-inducing molecules - rapamycin, all-trans retinoic acid, and butyrate - that targeted the mechanistic target of Rapa, the retinoid pathway, and histone deacetylase inhibition, respectively.

Fermented Food Tempeh Induces Interleukin 12 and Enhances Macrophage Phagocytosis

[Journal of Food Biochemistry] Researchers investigated the IL-12 inducibility of fermented foods using the specific antibody. Fermented soybean foods such as Tempeh and Natto are attracting attention in terms of nutrition, functionality, and food problems.

Phase II Evaluation of Stereotactic Ablative Radiotherapy (SABR) and Immunity in 11C-Choline-PET/CT-Identified Oligometastatic Castration-Resistant Prostate Cancer

[Clinical Cancer Research] Stereotactic ablative radiotherapy induces anti-tumor immunity in clinical and preclinical studies, but immunological biomarkers are lacking.

Popular