Tag results:
lymphoid cells
Extracellular Matrix News
A Fructosylated Peptide Derived from a Collagen II T Cell Epitope for Long-Term Treatment of Arthritis (FIA-CIA) in Mice
[Scientific Reports] Researchers investigated arthritis development in male DBA/1 mice which were injected with bovine collagen II and human fibrinogen on days 0 and 21, leading to stable and reproducible disease induction in 100% of immunized mice.
Immune Regulation News
Simultaneous Engagement of Tumor and Stroma Targeting Antibodies by Engineered NK-92 Cells Expressing CD64 Controls Prostate Cancer Growth
[Cancer Immunology Research] Investigators engineered a Natural Killer cell line to express CD64, the sole human high-affinity IgG Fcγ receptor, and bound these cells with antibodies to provide interchangeable tumor-targeting elements.
Prostate Cell News
Long-Term Expression Changes of Immune-Related Genes in Prostate Cancer after Radiotherapy
[Cancer Immunology] To identify long-term changes in gene expression after irradiation, PC3 and LNCaP prostate cancer cells were irradiated with either a single dose or a fractionated regimen of 10 fractions.
Prostate Cell News
Immunotherapy in Treatment of Metastatic Prostate Cancer: An Approach to Circumvent Immunosuppressive Tumor Microenvironment
[Prostate] The development of immunotherapy in cancer treatment has brought an exciting era of antiprostate cancer therapy through antitumor immune responses.
Intestinal Cell News
Antibody Secreting Cells Are Critically Dependent on Integrin α4β7/MAdCAM-1 for Intestinal Recruitment and Control of the Microbiota during Chronic Colitis
[Mucosal Immunology] β7 deficiency and MAdCAM-1 blockade specifically depleted antibody secreting cells from the colonic LP, leading to a fecal pan-immunoglobulin deficit, severe colitis, and alterations of microbiota composition.
Hematopoiesis News
An In Vivo Selection-Derived D-Peptide for Engineering Erythrocyte-Binding Antigens That Promote Immune Tolerance
[Proceedings of the National Academy of Sciences of the United States of America] Researchers investigated a straightforward approach based on erythrocyte binding to promote antigen-specific tolerance to both peptides and proteins, and showed that a fully D-chiral peptide library could be selected in vivo for the de novo discovery of a robust erythrocyte binder, which they attached to peptide and protein antigens.