lymphoid cells

[International Immunopharmacology] The authors investigated the effects of S1P receptor 1 (S1P1) specific S1P analogue SEW2871, S1P1 and S1P5 specific BAF312, and non-selective FTY720 on human Th17 and Treg differentiation and IL-23-mediated signaling.

[Cancer Discovery] Scientists described the identification and characterization of INCB086550, a novel, oral, small-molecule PD-L1 inhibitor.

[Periodontology 2000] Dendritic cells consist of multiple subsets that reside in the epithelium, connective tissues, and major organs.

[Science Translational Medicine] Vaccinated individuals who tested positive showed higher mucosal antibody responses in nasal secretions and higher Spike protein-specific CD8+ T cell responses in peripheral blood than did vaccinated individuals who tested negative.

[Journal of Experimental Medicine] Investigators found that the frequency of hepatitis B surface antigen (HBsAg)-specific CD8+ T cells was inversely correlated with expansion of monocytic myeloid-derived suppressor cells in young rather than in adult chronic hepatitis B patients.

[PLoS Pathogens] Investigators embarked on an epitope discovery study to define a CD8+ T cell landscape for HLA-A*11:01-expressing Indigenous and non-Indigenous Australian people.