Tag results:
lymphoid cells
Human Immunology News
Demethylase JMJD2D Induces PD-L1 Expression to Promote Colorectal Cancer Immune Escape by Enhancing IFNGR1-STAT3-IRF1 Signaling
[Oncogene] Scientists reported that both PD-L1 and JMJD2D were frequently overexpressed in human colorectal cancer specimens with a significant positive correlation.
Human Immunology News
Key Interactions in the Trimolecular Complex Consisting of the Rheumatoid Arthritis-Associated DRB1*04:01 Molecule, the Major Glycosylated Collagen II Peptide and the T Cell Receptor
[Annals of the Rheumatic Diseases] The crystal structures identified peptide binding to DRB1*04:01 and potential side chain exposure to T cells.
Human Immunology News
Adenosine Receptor A2a Blockade by Caffeine Increases IFN–Gamma Production in Th1 Cells from Patients with Rheumatoid Arthritis
[Scandinavian Journal of Rheumatology] Peripheral blood mononuclear cells were obtained from the peripheral blood of healthy individuals and patients with rheumatoid arthritis.
Human Immunology News
Flowcytometry in Reactive Lymph Node Aspirates: Evaluation of Distribution of Populations with Immunophenotypic Outliers
[Cytopathology] Flowcytometry of FNA/ scrape material from 30 cases of benign lymph nodes was evaluated to study the distribution of lymphoid populations and assess presence and percentages of immunophenotypic outliers.
Immunology of Infectious Disease News
MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses
[Journal of Immunology] Using miRNA microarray profiling, investigators characterized the expression profile of naive and in vivo generated murine effector antiviral CD8+ T cells.
Immune Regulation News
Androgen Receptor Signaling Promotes Treg Suppressive Function during Allergic Airway Inflammation
[Journal of Clinical Investigation] Using androgen receptor (AR) deficient and Foxp3 fate-mapping mice, researchers determined that AR signaling increased Treg suppression during Alternaria extract challenge by stabilizing Foxp3+ Tregs and limiting the number of ST2+ ex-Tregs and IL-13+ Th2 and ex-Tregs.