macrophages

[Molecular Therapy Oncolytics] Scientists explored the biological function of circSHKBP1 in NSCLC. CircSHKBP1 was found to be upregulated in NSCLC tissues and cell lines and was enriched in exosomes derived from NSCLC cells.

[Journal of Leukocyte Biology] Researchers showed that myeloid cells from cord blood could be activated to express T cell costimulatory markers, and also to produced Th1 promoting cytokines.

[Nature Communications] Investigators studied the live lung longitudinally and follow the fate of individual disseminated tumor cells that spontaneously disseminated from orthotopic breast tumors.

[Scientific Reports] Using in silico and in vitro techniques, investigators demonstrated heterogeneous expression of CD97, a leukocyte adhesion marker, in human glioblastoma.

[NPJ Regenerative Medicine] Isolated matrix-bound nanovesicles (MBV) were delivered via intravenous or peri-articular injection to rats with pristane-induced arthritis. The results of MBV administration were compared to intraperitoneal administration of methotrexate, the clinical standard of care.

[Cell Death & Disease] To investigate the role of myeloid cell MANF in the pathogenesis of AILI, researchers assayed serum and liver samples from acetaminophen-induced liver injury model mice and patients with drug-induced liver injury.