Tag results:
macrophages
Hematopoiesis News
SLAMF3 and SLAMF4 Are Immune Checkpoints That Constrain Macrophage Phagocytosis of Hematopoietic Tumors
[Science Immunology] Investigators reported a critical role of SLAM family receptors, ubiquitously expressed on hematopoietic cells and forming homotypic interactions, in constraining macrophage phagocytosis.
Human Immunology News
Pan-Cancer Analysis of GALNTs Expression Identifies a Prognostic of GALNTs Feature in Low Grade Glioma
[Journal of Leukocyte Biology] Investigators used Oncomine and The Cancer Genome Atlas databases to analyze the transcription and survival effect of N-acetylgalactosaminyltransferase genes (GALNTs) in pan-cancer.
Human Immunology News
Constructing a Novel Signature Based on Immune-Related lncRNA to Improve Prognosis Prediction of Cervical Squamous Cell Carcinoma Patients
[Reproductive Sciences] Researchers assessed the correlation between immune infiltration status, chemotherapeutics sensitivity, immune checkpoint proteins, and the signature.
Immunology of Infectious Disease News
DOCK2 Regulates Antifungal Immunity by Regulating RAC GTPase Activity
[Cellular & Molecular Immunology] Scientists reported that dedicator of cytokinesis 2 (DOCK2) promoted indispensable antifungal innate immune signaling and proinflammatory gene expression in macrophages.
Immune Regulation News
Myeloid Cell TBK1 Restricts Inflammatory Responses
[Proceedings of the National Academy of Sciences of the United States of America] The authors showed that TANK-binding kinase 1 (TBK1) served as a vital regulator of proinflammatory macrophage function and protected against tissue inflammation.
Immune Regulation News
M-CSF Supports Medullary Erythropoiesis and Erythroid Iron Demand Following Burn Injury through Its Activity on Homeostatic Iron Recycling
[Scientific Reports] The authors found M-CSF secretion was increased in burn patients and a murine model of post burn ACI, so they neutralized M-CSF in ACI mice to determine if erythropoiesis was improved.