Tag results:
macrophages
Immunology of Infectious Disease News
Vpr Counteracts the Restriction of LAPTM5 to Promote HIV-1 Infection in Macrophages
[Nature Communications] Investigators reported that Vpr counteracts lysosomal-associated transmembrane protein 5 (LAPTM5), a potent inhibitor of HIV-1 particle infectivity, to enhance HIV-1 infection in macrophages.
Umbilical & Placental Cell News
Placental Chorionic Plate-Derived Mesenchymal Stem Cells Ameliorate Severe Acute Pancreatitis by Regulating Macrophage Polarization via Secreting TSG-6
[Stem Cell Research & Therapy] The survival and colonization of exogenous placental chorionic plate-derived MSCs were observed by bioluminescence imaging and CM-Dil labeling in rodent animal models of severe acute pancreatitis.
Pulmonary Cell News
Single-Cell RNA Sequencing Identify SDCBP in ACE2-Positive Bronchial Epithelial Cells Negatively Correlates with COVID-19 Severity
[Journal of Cellular and Molecular Medicine] Since angiotensin-converting enzyme 2 (ACE2)-positive cells were hosts for COVID-19, researchers focussed on this cell type to explore the underlying mechanisms of COVID-19.
Pulmonary Cell News
AMPK Activates Parkin Independent Autophagy and Improves Post Sepsis Immune Defense against Secondary Bacterial Lung Infections
[Scientific Reports] Scientists showed acquired Parkin and AMPK deficiency in leukocytes of post-sepsis immunosuppression from human subjects and mice.
ESC & iPSC News
Shoreline Biosciences and BeiGene Announce Strategic Worldwide Collaboration to Develop and Commercialize Genetically Modified Natural Killer (NK) Cell Therapies
[nan] Shoreline Biosciences, Inc. and BeiGene, Ltd. announced a worldwide collaboration to develop and commercialize a portfolio of natural killer (NK)-based cell therapeutics with Shoreline’s iPSC NK cell technology and BeiGene’s research and clinical development capabilities for different malignancies.
Human Immunology News
Tissue-Resident Macrophages Provide a Pro-Tumorigenic Niche to Early NSCLC Cells
[Nature] Researchers identified distinct populations of macrophages that were enriched in human and mouse lung tumors.