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mass spectrometry

Prenatal Exposure to Poly-/Per-Fluoroalkyl Substances Is Associated with Alteration of Lipid Profiles in Cord-Blood

[Metabolomics] Researchers combined determination of bile acids and molecular lipids by liquid chromatography with ultra-high-resolution mass spectrometry, and separately quantified cord blood concentrations of sixteen poly-/per-fluoroalkyl substances in a cohort of Chinese infants in a cross-sectional study.

Interactions between Gastric Microbiota and Metabolites in Gastric Cancer

[Cell Death & Disease] Scientists characterized the gastric microbiome and metabolome profiles of 37 gastric cancer tumor tissues and matched non-tumor tissues using 16s rRNA gene sequencing and ultrahigh performance liquid chromatography tandem mass spectrometry, respectively.

The Photoprotective Properties of α-Tocopherol Phosphate against Long-Wave UVA1 (385 nm) Radiation in Keratinocytes In Vitro

[Scientific Reports] Researchers investigated if α-tocopherol phosphate, a promising new antioxidant, could protect against long-wave UVA1 induced cell death and scavenge UVA1 induced reactive oxygen species in a skin cell model.

Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses

[Circulation Research] The authors identified the protein syndesmos to specifically interact with cZNF292 in endothelial cells by RNA affinity purification and subsequent mass spectrometry analysis.

The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma

[Hepatology] High-throughput RNA-seq was used to identify the differentially expressed circRNAs upon IL-6 stimulation in intrahepatic cholangiocarcinoma cells.

Improving Motor Neuron-Like Cell Differentiation of hEnSCs by the Combination of Epothilone B Loaded PCL Microspheres in Optimized 3D Collagen Hydrogel

[Scientific Reports] Providing a 3D permissive environment with epothilone B significantly improved motor neuron-like cell differentiation and maturation of human endometrial stem cells (hEnSCs) and was a promising approach to replace lost neurons after spinal cord injury.

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