mass spectrometry

[iScience] Scientists mapped the subcellular reorganization of the proteome of human keratinocytes in response to UVA light.

[Scientific Reports] Scientists evaluated the impact of morphine exposure at three different concentrations for 24 hours and 48 hours on primary human brain microvascular endothelial cells.

[Scientific Reports] Researchers examined blood–brain barrier disruption, by assessing brain-derived neurotropic factor, neuron-specific enolase levels, and gut-blood barrier disruption by trimethylamine N-oxide in chronic kidney disease patients.

[Frontiers in Oncology] Investigators revealed that PLA2G6 was up-regulated in cutaneous malignant melanoma tissues compared to nevus tissues, as well as increased in vitro in SK-MEL-28 and M14 melanoma cell lines compared to human melanocytes.

[Cell Reports] Investigators established that identification of the comprehensive miRNA targetome within primary cells enabled discovery of genes and molecular networks underpinning stemness properties of normal and leukemic cells.

[Cancer Letters] By combining organoids technology with Click-chemistry coupled Mass Spectrometry, investigators demonstrate a prominent role of ERG in remodeling the protein secretome of prostate progenitors.