mesenchymal stem cells

[Environmental Science and Pollution Research] Scientists investigated the effect of Bisphenol A and diethylhexyl phthalate on the clonogenic capacity of umbilical cord blood HSCs.

[Nature Biomedical Engineering] The authors showed that high-mannose N-linked glycans could serve as a biomarker for the label-free tracking of transplanted human mesenchymal stem cells by mannose-weighted chemical exchange saturation transfer magnetic resonance imaging.

[Biomedical Journal] In a bid to consider mesenchymal stem cells and their secretome as a therapeutic regenerative approach for idiopathic male infertility, the authors focus on the rationale of spermatogonial stem cell niche injury modeling.

[NorthSea Therapeutics B.V.] NorthSea Therapeutics B.V. announced it has initiated a Phase I study with SEFA-6179 in adult subjects, targeting the initial orphan indication of the treatment of intestinal failure associated liver disease.

[Journal of Biomedical Materials Research Part B-Applied Biomaterials] A transwell migration assay was used to investigate recruitment of MDA-MB-231, MCF-7, and MDA-MB-453 breast cancer cells to the osseous polycaprolactone-nano-hydroxyapatite scaffolds.

[Cancer Gene Therapy] Researchers demonstrated that bone marrow MSC-derived extracellular vesicles carrying NEAT1 could promote the progression of melanoma by inducing M2 polarization of macrophages, and thus may be considered as a potential target for melanoma therapeutics.