mesenchymal stem cells

[Biofactors] A series of experiments were performed to systematically investigate the cellular behavior of growth hormone (GH)/GH receptor (GHR) in MSCs, and the results showed that GH/GHR not only internalized into the cytoplasm, but also transported into the cell nuclei of MSCs.

[Cytotherapy] The allorejection of MSCs indicates that they are not fully immune-privileged. The authors investigated the immunogenicity of human adipose-derived MSCs and identified potential immunogenic molecules.

[European Journal of Pharmacology] Scientists review MSC-based nanocomposite's current approaches and compared their advantages and limitations for building effective regenerative medicines.

[NPJ Regenerative Medicine] The authors suggested that mesenchymal stromal cells ameliorated surgery-induced hepatocellular stress and epithelial-mesenchymal transition, thus supporting epithelial integrity and facilitating regeneration.

[Aging] Researchers underscored the effect of maternal age on the biological characteristics and stemness properties of placenta-derived mesenchymal stem cells.

[Experimental Cell Research] To explore the role of human umbilical cord mesenchymal stem cells (hucMSCs) in inhibiting endothelial inflammation in Kawasaki disease (KD), the effects of hucMSCs on the expression of CD54 and CD105 in endothelial cells in KD were analyzed in vivo and in vitro.