Tag results:
mesenchymal stem cells
Extracellular Matrix News
Programmable and Contractile Materials through Cell Encapsulation in Fibrous Hydrogel Assemblies
[Science Advances] Researchers developed fibrous hydrogel assemblies that were stabilized with photocrosslinking and displayed fiber density–dependent strain-responsive properties.
Cancer Stem Cell News
Noncanonical Roles of p53 in Cancer Stemness and Their Implications in Sarcomas
[Cancer Letters] The authors address the noncanonical roles of p53 and their implications in sarcoma initiation and progression.
Mesenchymal Cell News
Single-Cell RNA-Seq of Out-of-Thaw Mesenchymal Stromal Cells Shows Tissue-of-Origin Differences and Inter-Donor Cell-Cycle Variations
[Stem Cell Research & Therapy] The authors showed that donor differences in human MSC (hMSC) transcriptome were minor relative to the intrinsic differences in tissue-of-origin. hMSCs with different transcriptomic profiles showed potential differences in functional characteristics.
Mesenchymal Cell News
PPARβ/δ Accelerates Bone Regeneration in Diabetic Mellitus by Enhancing AMPK/mTOR Pathway-Mediated Autophagy
[Stem Cell Research & Therapy] Investigators explored the effects of PPARβ/δ agonist on the regeneration of diabetic bone defects and the osteogenic differentiation of rat bone marrow MSCs under a pathological high-glucose condition.
Mesenchymal Cell News
Engineered Small Extracellular Vesicles as a FGL1/PD-L1 Dual-Targeting Delivery System for Alleviating Immune Rejection
[Advanced Science] Among various cell sources, FGL1/PD-L1 small extracellular vesicles (sEVs) derived from MSCs not only enriched FGL1/PD-L1 expression but also maintained the immunomodulatory properties of unmodified MSC sEVs.
Mesenchymal Cell News
Transplantation of Rat Cranial Bone-Derived Mesenchymal Stem Cells Promotes Functional Recovery in Rats with Spinal Cord Injury
[Scientific Reports] Scientists determined the effect of transplanting rat cranial bone-derived MSCs (rcMSCs) in rat spinal cord injury models. The transplantation of rcMSCs improved motor function and electrophysiology recovery, and reduced cavity ratio.