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mesenchymal stem cells

A Functional Extracellular Matrix Biomaterial Enriched with VEGFA and bFGF as Vehicle of Human Umbilical Cord Mesenchymal Stem Cells in Skin Wound Healing

[Biomedical Materials] The authors prepared a functional cell derived extracellular matrix biomaterial enriched with VEGFA and bFGF, which induced endothelial differentiation of human umbilical cord MSCs and promoted angiogenesis, which may improve the healing effect of skin injury.

Self-Renewal or Quiescence? Orchestrating the Fate of Mesenchymal Stem Cells by Matrix Viscoelasticity via PI3K/Akt-CDK1 Pathway

[Biomaterials] Researchers established an alginate hydrogel system with constant stiffness and tunable stress relaxation rate, which was a key parameter for the viscoelastic property of the material.

Advances in Mesenchymal Stem Cell Conditioned Medium-Mediated Periodontal Tissue Regeneration

[Journal of Translational Medicine] Scientists discuss the accumulating evidence indicating the therapeutic potential of the MSC-conditioned medium in periodontal regeneration-related pre-clinical and clinical studies.

Mesenchymal Stem Cells in Cancer Progression and Anticancer Therapeutic Resistance

[Cancer Cell International] The authors analyze the existing researches and elaborate on the functions of MSCs in cancer progression and anticancer therapeutic resistance, demonstrating that MSCs may be a viable cancer therapeutic target.

A Fluid-Powered Refillable Origami Heart Pouch for Minimally Invasive Delivery of Cell Therapies in Rats and Pigs

[Med] Scientists developed a fluid-driven heart pouch with a memory-shaped microfabricated lattice structure inspired by origami. The pore size of the membrane was around 0.4 μm, which allowed for the penetration of growth factors and exosomes.

Stem Cell-Based Therapy for COVID-19 and ARDS: A Systematic Review

[NPJ Regenerative Medicine] Scientists performed a systematic review of clinical studies investigating different types of stem cells as treatments for COVID-19 and ARDS to evaluate the safety and potential efficacy of cell therapy.

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