mesenchymal stem cells

[Stem Cell Reviews and Reports] Scientists found that pharmacological inhibition of NF-κB pathway in both control and CoCl2-treated mesenchymal stromal cells completely blocked their intercellular communication with the co-cultured HSCs and progenitor cells, resulting in an extremely poor output of hematopoietic cells.

[Cell Death & Disease] The authors investigated the mechanism of bone marrow MSC-derived exosome using high phosphate stimulated human aortic smooth muscle cells and 5/6 subtotal nephrectomy rat models.

[Cell and Tissue Research] Human umbilical cord-derived MSCs were subcutaneously injected into mice with imiquimod-induced psoriasis-like skin inflammation to explore the feasibility of this cellular therapy.

[Stem Cell Reviews and Reports] Scientists summarize the biological effects and mechanisms of action of MSCs, elucidating recent clinical trials phases and findings, and highlighting therapeutic effects of MSCs in several representative diseases

[ACS Biomaterials Science & Engineering] Scientists covalently modified alginate with RGD and QK peptides that were injected subcutaneously into immunocompetent mice.

[Journal of Cellular Biochemistry] Scientists investigated the decoy receptor osteoprotegerin axis and determined the effect of exendin-4 upon adipose MSC osteogenic differentiation.