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mesenchymal stem cells

3D Bioprinted Silk Fibroin Hydrogels for Tissue Engineering

[Nature Protocols] Investigators developed a methacrylated photocurable silk fibroin bioink for digital light processing 3D bioprinting to generate structures with high mechanical stability and biocompatibility for tissue engineering applications.

The Regulatory Effect of Hyaluronan on Human Mesenchymal Stem Cells’ Fate Modulates Their Interaction with Cancer Cells In Vitro

[Scientific Reports] Investigators explored breast cancer and glioblastoma multiforme cell lines MDA-MB-321 and U87-MG, and evaluated the impact of hyaluronan on tumor promoting features of bone marrow-derived mesenchymal stem cells, and their interaction with tumor cells.

Mechanics-Driven Nuclear Localization of YAP Can Be Reversed by N-Cadherin Ligation in Mesenchymal Stem Cells

[Nature Communications] Researchers developed a material and culture system for modifying and measuring the degree to which cells retained cumulative effects of mechanosensing.

Lung Mesenchymal Stromal Cells Influenced by Th2 Cytokines Mobilize Neutrophils and Facilitate Metastasis by Producing Complement C3

[Nature Communications] The authors found that lung mesenchymal stromal cells at pre-metastatic stage possess potent metastasis-promoting activity.

Lung Mesenchymal Stromal Cells Influenced by Th2 Cytokines Mobilize Neutrophils and Facilitate Metastasis by Producing Complement C3

[Nature Communications] Pre-metastatic niche formation is critical for the colonization of disseminated cancer cells in distant organs. Researchers found that lung mesenchymal stromal cells at pre-metastatic stage possess potent metastasis-promoting activity.

Intramuscular Injection of Mesenchymal Stem Cells Activates Anabolic and Catabolic Systems in Mouse Skeletal Muscle

[Scientific Reports] Researchers measured changes in mechanistic target of rapamycin complex 1 signaling, the ubiquitin–proteasome system, and autophagy-lysosome system-related factors after a single intramuscular injection of MSCs with green fluorescence protein into mouse muscles.

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