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mesenchymal stem cells

Conquering the Cytokine Storm in COVID-19-Induced ARDS Using Placenta-Derived Decidua Stromal Cells

[Journal of Cellular and Molecular Medicine] Researchers conducted a safety and efficacy study that included ten patients with a median age of 50 years with COVID-19-induced acute respiratory distress syndrome (ARDS).

Cynata Signs a Landmark New Strategic Partnership Agreement with Fujifilm

[Kalkin Media] Cynata Therapeutics Limited has entered into a new strategic partnership with Fujifilm Corporation which includes detailed and agreed core terms for Fujifilm to provide clinical & commercial manufacturing services for, as well as supply of, the vompany’s Cymerus™ therapeutic MSC products.

Transcriptomic Profiling and Functional Prediction Reveal Aberrant Expression of Circular RNAs during Osteogenic Differentiation in Human Umbilical Cord Mesenchymal Stromal Cells

[Scientific Reports] Investigators analyzed RNA-sequence data to reveal expression profiles of circRNAs during osteogenesis of human umbilical cord MSCs, then elucidated the underlying mechanisms of action.

Additional Benefit of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Therapy on Sepsis Syndrome-Associated Acute Kidney Injury in Rat Treated with Antibiotic

[Stem Cell Research & Therapy] Investigators tested whether human induced-pluripotent stem-cell-derived mesenchymal-stem-cells would offer an additional benefit to the rodent with acute kidney injury associated sepsis syndrome undergoing ciprofloxacin therapy.

Mesenchymal Stromal Cells: Putative Microenvironmental Modulators Become Cell Therapy

[Cell Stem Cell] Scientists discuss potential mechanisms of action for the therapeutic effects of MSC transplantation, experimental models that dissect tissue modulating function of MSCs, and approaches for identifying MSC effects in vivo by integrating biomarkers of disease and MSC activity.

The Interaction of Helicobacter pylori with Cancer Immunomodulatory Stromal Cells: New Insight into Gastric Cancer Pathogenesis

[Seminars in Cancer Biology] The authors discuss the interplay between H. pylori and tumor-supportive cells, including mesenchymal stem cells, cancer-associated fibroblasts, tumor-associated macrophages, and myeloid derived-suppressor cells in gastric cancer.

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