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mesenchymal stem cells

Mesenchymal Stromal Cells for Enhancing Hematopoietic Engraftment and Treatment of Graft-Versus-Host Disease, Hemorrhages and Acute Respiratory Distress Syndrome

[Frontiers in Immunology] The authors summarize current evidence from in vitro studies, animal models, and their clinical experience, to support stromal cell therapy in multiple clinical indications.

Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Containing NORAD Promote Osteosarcoma by miR-30c-5p

[Laboratory Investigation] Investigators explored the role of non-coding RNA activated by DNA damage (NORAD) derived from extracellular vesicles of bone MSCs in osteosarcoma.

MicroRNA-378 Contributes to Osteoarthritis by Regulating Chondrocyte Autophagy and Bone Marrow Mesenchymal Stem Cell Chondrogenesis

[Molecular Therapy-Nucleic Acids] MiR-378 amplified osteoarthritis (OA) development via repressing chondrocyte autophagy and by inhibiting bone marrow MSC chondrogenesis, thus indicating miR-378 may be a potential therapeutic target for OA treatments.

3D Printing of Ti3C2-MXene-Incorporated Composite Scaffolds for Accelerated Bone Regeneration

[Biomedical Materials] Ti3C2 MXene was incorporated into composite scaffolds composed of hydroxyapatite and sodium alginate via extrusion-based 3D printing to evaluate its potential in bone regeneration.

IMAC Holdings, Inc. Announces Initiation of Third and Final Cohort of its Phase I Clinical Study of Umbilical Cord-Derived Mesenchymal Stem Cells for the...

[IMAC Holdings, Inc. (] IMAC Holdings, Inc. announced it has initiated the third and final cohort of its Phase I clinical trial for its investigational compound utilizing umbilical cord-derived allogenic mesenchymal stem cells for the treatment of bradykinesia due to Parkinson’s disease.

Lack of Tumorigenesis and Protumorigenic Activity of Human Umbilical Cord Mesenchymal Stem Cells in NOD SCID Mice

[BMC Cancer] Researchers observed tumor formation in NOD SCID mice after a single subcutaneous injection of human umbilical cord-MSCs and the effect of these cells on tumor growth in tumor-bearing mice.

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