mesenchymal stem cells

[Biomedical Materials] Researchers developed a double crosslinked alginate hydrogel for 3D bioprinting, and human umbilical cord MSCs could differentiate into chondrocytes on its printed 3D scaffold after four weeks' culture.

[Stem Cell Research & Therapy] A well-established concanavalin A-induced fulminant hepatitis mouse model was used to investigate the effects of transplanting human umbilical cord Wharton's jelly-derived MSCs on fulminant hepatitis.

[Journal of Nanobiotechnology] Scientists constructed CD73 modified extracellular vesicles and explored the anti-inflammatory effects after spinal cord injury. CD73 engineered extracellular vesicles were derived from human umbilical cord MSCs transduced by lentiviral vectors to upregulate the expression of CD73.

[Cell Death Discovery] The authors showed dual regulatory functions of bone marrow-derived mesenchymal stem cells in attenuating hepatic fibrosis by promoting Ly6Chi/Ly6Clo subset conversion and Ly6Clo macrophage restoration through secreting antifibrogenic-cytokines and activating the apoptotic pathway.

[Stem Cell Research & Therapy] Scientists reported that both human amniotic stem cells and their conditional medium had a potent anti-hyperpigmentation in skin in vivo and in vitro.

[Scientific Reports] Researchers separated chicken bone marrow-derived mesenchymal stem cells (BM-MSCs); investigated whether BM-MSCs could improve lipopolysaccharide-induced lung and distal organ injury; and explored the underlying mechanisms.