mesenchymal stem cells

[Biomacromolecules] Scientists presented two series of fibrous and porous hydrogels and used them as substrates to study the mechanoresponses of bone marrow MSCs to stiffness and fibrous structure.

[Stem Cell Research & Therapy] In a wound healing mouse model, the histological evaluation of wound tissue in PBS, bone marrow MSCs (BMSCs), and ascorbic acid 2-glucoside-treated BMSCs group were investigated.

[Stem Cell Research & Therapy] Human umbilical cord-derived MSCs infusions improved systemic metabolic homeostasis and alleviated insulin resistance in epididymal adipose tissue but elicited no change in weight.

[Molecular Therapy-Oncolytics] Scientists explored the general characteristics of MSC as delivery tools for cancer therapeutic agents and discuss the potential of oncolytic viruses (OV) as immune therapeutics.

[Ossium Health, Inc. (Business Wire, Inc.)] Ossium Health, Inc. announced that the US FDA has accepted its Investigational New Drug application for OSSM-001, an MSC product, for the treatment of refractory perianal fistulas in patients with Crohn’s disease.

[Scientific Reports] Scientists directed human Wharton's jelly-MSCs chondrogenesis using micropattern made of spidroin bioink as opposed to fibronectin that often was used as the gold standard.