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mesenchymal stem cells
Umbilical & Placental Cell News
CHIP-Overexpressing Wharton’s Jelly-Derived Mesenchymal Stem Cells Attenuate Hyperglycemia-Induced Oxidative Stress-Mediated Kidney Injuries in Diabetic Rats
[Free Radical Biology and Medicine] Western blot analysis, flow cytometry, and MitoSOX staining revealed that hyperglycemia-induced mitochondrial oxidative stress production and apoptosis were attenuated in CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells
Umbilical & Placental Cell News
Mesenchymal Stem Cell-Derived Extracellular Vesicles as Probable Triggers of Radiation-Induced Heart Disease
[Stem Cell Research & Therapy] Scientists examined the hypothesis that the altered secretion of extracellular vesicles from MSCs was the trigger of radiation-induced heart disease.
Umbilical & Placental Cell News
Unresponsive Thin Endometrium Caused by Asherman Syndrome Treated with Umbilical Cord Mesenchymal Stem Cells on Collagen Scaffolds: A Pilot Study
[Stem Cell Research & Therapy] Researchers evaluate the effect of transplantation with collagen scaffold/umbilical cord MSCs on Asherman syndrome.
Umbilical & Placental Cell News
hucMSC-Derived Exosomes Attenuate Colitis by Regulating Macrophage Pyroptosis via the miR-378a-5p/NLRP3 Axis
[Stem Cell Research & Therapy] Human umbilical cord MSC-derived exosomes carrying miR-378a-5p inhibited NLRP3 inflammasomes and abrogated cell pyroptosis to protect against DSS-induced colitis.
Mesenchymal Cell News
The Use of Umbilical Cord-Derived Mesenchymal Stem Cells in Patients with Muscular Dystrophies: Results from Compassionate Use in Real-life Settings
[Stem Cells Translational Medicine] The authors administered advanced therapy medicinal product containing umbilical cord-derived MSCs to 22 patients with muscular dystrophies.
Mesenchymal Cell News
MicroRNA-26a Shuttled by Extracellular Vesicles Secreted from Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Damage through KLF9-Mediated Regulation of TRAF2/KLF2 Axis
[Adipocyte] Researchers investigated the role of miR-26a shuttled by extracellular vesicles derived from adipose-derived MSCs in neuronal damage.
