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mesenchymal stem cells

Human Adipose-Derived Mesenchymal Stromal Cells From Face and Abdomen Undergo Replicative Senescence and Loss of Genetic Integrity After Long-term Culture

[Experimental Cell Research] The authors evaluated long-term culture of human facial adipose-derived MSCs (fASCs) and abdominal ASCs and showed that both met the criteria for MSC characterization but presented differences in their immunophenotypic profile, and differentiation and clonogenic potentials.

PDGF-BB/SA/Dex Injectable Hydrogels Accelerate BMSC-Mediated Functional Full Thickness Skin Wound Repair by Promoting Angiogenesis

[Journal of Materials Chemistry B] Scientists showed that the Platelet derived growth factor-BB (PDGF-BB)/sodium alginate (SA)/dextran (Dex) hydrogels could sustainably release PDGF-BB with excellent biocompatibility in vitro and in vivo.

Osteogenic and Angiogenic Potency of VEGF165-Transfected Canine Bone Marrow Mesenchymal Cells Combined with Coral Hydroxyapatite in Vitro

[Tissue Engineering and Regenerative Medicine] Investigators explored the osteogenic and angiogenic potential of human vascular endothelial growth factor 165 (hVEGF165) gene-transfected canine bone marrow MSCs combined with coral hydroxyapatite scaffold.

Effect of Adipose Derived Mesenchymal Stem Cells on Multiple Organ Injuries in Diet-Induced Obese Mice

[Tissue Barriers] Scientists studied the effect of adipose-derived MSCs on obesity-induced multi-organ injuries in a diet-induced obese mouse model.

Bone Marrow-Mesenchymal Stem Cell-Derived Exosomal microRNA-141 Targets PTEN and Activates β-Catenin to Alleviate Myocardial Injury in Septic Mice

[Immunopharmacology and Immunotoxicology] The authors revealed the function of bone marrow MSC-derived exosomes in sepsis-induced myocardial injury and the molecular mechanism.

Mesenchymal Stem Cell Extracellular Vesicles as Adjuvant to Bone Marrow Stimulation in Chondral Defect Repair in a Minipig Model

[Cartilage] Investigators evaluated the effects of MSC-extracellular vesicles on chondrocyte proliferation in vitro and on cartilage repair in vivo following bone marrow stimulation of focal chondral defects of the knee.

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