monocytes

[Immunity] Scientists examined the mechanisms that control bacterial infection in the peritoneum using a mouse model of abdominal sepsis following intraperitoneal Escherichia coli infection.

[Cell Reports] The authors suggested that infiltrative monocytes promoted fibrogenesis in nonalcoholic fatty liver disease via ADA2-mediated autocrine/paracrine signaling culminating in enhanced PDGF-B production.

[iScience] To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes across different nonalcoholic fatty liver disease stages were profiled, identifying hepatocytes and 12 other non-parenchymal cell types.

[Cell Discovery] Scientists reported, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an inactivated SARS-CoV-2 vaccine.

[Blood] The authors assessed the effects of Nox2 absence on monocyte-derived macrophages in gp91phox-/y mice during zymosan-induced peritonitis.

[Cell Death & Disease] Scientists evidenced that extracellular vesicles secreted from human hepatocytes attenuated the CCL4-induced acute liver injury by inhibiting the recruitment of monocytes through downregulation of chemokine receptor in the bone marrow and recruitment of neutrophils through the reduction of C-X-C motif chemokine ligand 1 (CXCL1) and CXCL2 expression levels in the liver.