Tag results:
monocytes
Immune Regulation News
Human Invariant Natural Killer T Cells Promote Tolerance by Preferential Apoptosis Induction of Conventional Dendritic Cells
[Haematologica] Dendritic cells were either generated from monocytes or isolated directly from blood of healthy donors or graft-versus-host disease patients and co-cultured in a mixed lymphocyte reaction with T cells obtained from healthy donors or transplantation bags.
Human Immunology News
Cytosolic dsRNA Improves Neonatal Innate Immune Responses to Adjuvants in Use in Pediatric Vaccines
[Journal of Leukocyte Biology] Researchers showed that myeloid cells from cord blood could be activated to express T cell costimulatory markers, and also to produced Th1 promoting cytokines.
Extracellular Matrix News
Immunomodulatory Matrix-Bound Nanovesicles Mitigate Acute and Chronic Pristane-Induced Rheumatoid Arthritis
[NPJ Regenerative Medicine] Isolated matrix-bound nanovesicles (MBV) were delivered via intravenous or peri-articular injection to rats with pristane-induced arthritis. The results of MBV administration were compared to intraperitoneal administration of methotrexate, the clinical standard of care.
Hepatic Cell News
Mesencephalic Astrocyte-Derived Neurotrophic Factor Reprograms Macrophages to Ameliorate Acetaminophen-Induced Acute Liver Injury via p38 MAPK Pathway
[Cell Death & Disease] To investigate the role of myeloid cell MANF in the pathogenesis of AILI, researchers assayed serum and liver samples from acetaminophen-induced liver injury model mice and patients with drug-induced liver injury.
Extracellular Matrix News
Mesenchymal Stromal Cell-Derived Septoclasts Resorb Cartilage during Developmental Ossification and Fracture Healing
[Nature Communications] Scientists showed that matrix degradation and chondrocyte phagocytosis were mediated by fatty acid binding protein 5-expressing cells representing septoclasts, which had a mesenchymal origin and were not derived from hematopoietic cells.
Human Immunology News
NLRP3 Inflammasome Activation in Human Peripheral Blood Mononuclear Cells Induced by Venoms Secreted PLAM2s
[International Journal of Biological Macromolecules] Peripheral blood mononuclear cells were isolated by density gradient and incubated with RPMI, LPS, BthTX-I or BthTX-II isolated from Bothrops jararacussu venom, to evaluate viability, and the results showed that there was no cell death.