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myeloid cells

The Severity of Glomerular Endothelial Cell Injury Is Associated with Infiltrating Macrophage Heterogeneity in Endocapillary Proliferative Glomerulonephritis

[Scientific Reports] The authors examined 42 renal biopsy samples representing endocapillary proliferative lesions from post-streptococcal acute glomerulonephritis, Henoch–Schönlein purpura nephritis, and lupus nephritis

Inherited PD-1 Deficiency Underlies Tuberculosis and Autoimmunity in a Child

[Nature Medicine] Investigators studied a patient with inherited PD-1 deficiency and tuberculosis who died of pulmonary autoimmunity. The patient’s leukocytes did not express PD-1 or respond to PD-1-mediated suppression.

Accelerated Burn Wound Healing with Photobiomodulation Therapy Involves Activation of Endogenous Latent TGF-β1

[Scientific Reports] Researchers investigated the roles of individual cell types involved in burn wound healing following photobiomodulation (PBM) treatments and noted discrete effects on epithelieum, fibroblasts, and macrophage functions.

Decreased Ferroportin in Hepatocytes Promotes Macrophages Polarize towards an M2-Like Phenotype and Liver Fibrosis

[Scientific Reports] Ferroportin downregulation in hepatic cells increased the levels of the M2 markers CD206, TGF- β, VEGF, MMP-9, Laminin, Collagen, IL-4 and IL-10.

Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

[Journal of Bone and Mineral Research] Scientists provided evidence of the in vivo function of MMP-10 during endochondral ossification and defined the macrophages as the lead cell population in cartilage removal and vascular invasion.

Post-Match Recovery Profile of Leukocyte Cell Subsets among Professional Soccer Players

[Scientific Reports] Participants playing up to 540 in cumulative match time and less than 30 min in each single match during the observation period formed the control group. White blood cell phenotyping and creatine kinase plasma activity analyses were performed.

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