myeloid cells

[Cell Death & Disease] The pancreas was analyzed by histology, immunochemistry staining, and TUNEL assays, and the expression of certain proteins and RNAs, cytokine levels, trypsin activity, and reactive oxygen species (ROS) levels were determined.

[Scientific Reports] The authors analyzed the profiling of immune cells in the peripheral blood of steroid-sensitive nephrotic syndrome patients and steroid-resistant nephrotic syndrome patients before and after standard steroid treatment to clarify the immunological mechanism of nephrotic syndrome patients.

[Blood Advances] Investigators enrolled 38 patients with hematologic malignancies scheduled to undergo MMUD-HCT onto 1 of 2 conditioning strata: myeloablative using fludarabine and fractionated total body irradiation or reduced intensity with fludarabine/melphalan.

[Xenotransplantation] The authors generated a rat xenotransplantation model to prove the role of macrophages as a xenotransplantation barrier. Immunodeficiency in SRG rats, which were Sprague–Dawley rats lacking Rag2 and Il2rg, was confirmed by flow cytometry and spleen immunostaining.

[Science Translational Medicine] To examine the ontogeny and function of MS1 cells, researchers developed a cellular model for inducing CD14+ MS1 monocytes from healthy bone marrow hematopoietic stem and progenitor cells.

[Signal Transduction and Targeted Therapy] Aberrant bone marrow-M1/M2 MФ polarization, characterized by increased M1 MФs and decreased M2 MФs and accompanied by impaired megakaryopoiesis-supporting abilities, was found in patients with thrombocytopenia post-allotransplant.