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myeloid cells

Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation

[Circulation Research] Mouse models of atherosclerosis in endothelial cell-specific-Bach1 knockout mice were used to study the role of BTB and CNC homology 1 (BACH1) in the regulation of atherogenesis and the underlying mechanisms.

Influence of Trichomonas vaginalis Macrophage Migration Inhibitory Factor on the Proliferation Activity of Prostate Epithelial Cell Line and Its Preliminary Mechanism

[andrology] The authors determined the influence of macrophage Trichomonas vaginalis macrophage migration inhibitory factor on prostate epithelial cells and its preliminary mechanism.

Qi Ling Decreases Paclitaxel Resistance in the Human Prostate Cancer by Reversing Tumor-Associated Macrophages Function

[Aging] Investigators administrated Qi Ling (QL) to rats and collected the serum from QL-treated rats and established the co-culture system of tumor-associated macrophages/paclitaxel resistant prostate cancer cells.

Antiplatelet Antibody Predicts Platelet Desialylation and Apoptosis in Immune Thrombocytopenia

[Haematologica] Researchers used sera from 61 immune thrombocytopenia patients and assessed the capacity of antiplatelet antibodies to induce neuraminidase 1 surface expression, RCA-1 lectin binding and loss of mitochondrial inner membrane potential on donors’ platelets.

Revealing the Transcriptional Heterogeneity of Organ-Specific Metastasis in Human Gastric Cancer Using Single-Cell RNA Sequencing

[Clinical and Translational Medicine] Ten fresh human tissue samples from six patients, including primary tumor and adjacent non-tumoral samples and six metastases from different organs or tissues were evaluated using single-cell RNA sequencing.

Targeting Polarized Phenotype of Microglia via IL6/JAK2/STAT3 Signaling to Reduce NSCLC Brain Metastasis

[Signal Transduction and Targeted Therapy] Scientists indicated that targeting IL6/JAK2/STAT3 signaling in activated microglia might be a promising new approach for inhibiting brain metastasis in NSCLC patients.

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