Tag results:

myeloid cells

Severity of Thermal Burn Injury Is Associated with Systemic Neutrophil Activation

[Scientific Reports] Leukocyte, platelet, neutrophil, and lymphocyte counts were assessed. Scientists analyzed the association of neutrophil-derived factors with clinical severity scoring systems.

TIM-3 Shuttled by MV3 Cells-Secreted Exosomes Inhibits CD4+ T Cell Immune Function and Induces Macrophage M2 Polarization to Promote the Growth and Metastasis of...

[Translational Oncology] Silencing of TIM-3 shuttled by MV3 cells-derived exosomes improved CD4+ T cell immune function and inhibited macrophage M2 polarization to attenuate the growth and metastasis of melanoma cells.

Mesenchymal Stromal Cell-Derived Septoclasts Resorb Cartilage during Developmental Ossification and Fracture Healing

[Nature Communications] Scientists showed that matrix degradation and chondrocyte phagocytosis were mediated by fatty acid binding protein 5-expressing cells representing septoclasts, which had a mesenchymal origin and were not derived from hematopoietic cells.

Characterizing Cellular Heterogeneity in Fibrotic Hypersensitivity Pneumonitis by Single-Cell Transcriptional Analysis

[Cell Death Discovery] Utilizing an integrated strategy based on scRNA-seq, scTCR-seq, and bulk RNA-seq analysis of fibrotic hypersensitivity pneumonitis profiles, the authors identified ten major cell types and 19 unique subtypes.

Tumor-Associated Neutrophils Secrete AGR2 to Promote Colorectal Cancer Metastasis via Its Receptor CD98hc–xCT

[Gut] Scientists investigated the cellular source for secreted anterior gradient-2 (AGR2) in the tumor microenvironment and underlying mechanisms mediating secreted AGR2’s effects.

Integrative Bioinformatics and Experimental Analysis Revealed TEAD as Novel Prognostic Target for Hepatocellular Carcinoma and Its Roles in Ferroptosis Regulation

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

Popular