myeloid cells

[Scientific Reports] Investigators asked whether CCR2 was necessary for the development of colitis in mice lacking the receptor for IL10.

[Journal of Experimental Medicine] Scientists identified alveolar macrophage progenitors in human fetal liver that expressed the GM-CSF receptor CD116 and the transcription factor MYB.

[Cell Death & Disease] Knockdown of MnSOD inhibited TNBC cell invasion, breast cancer stem cells, mitochondrial reactive oxygen species, and interleukin-6 excretion promoted by multiple copies in T cell malignancy-1.

[Mucosal Immunology] Scientists discuss recent developments in our understanding of lung macrophage heterogeneity, ontogeny, metabolism and function in the context of health and disease, and highlight core conceptual advances and key unanswered questions that we believe should be focus of work in the coming years.

[Stem Cell Reviews and Reports] Scientists investigated immunomodulatory effects of a novel mesenchymal stem cell product in mouse endotoxemia and polymicrobial sepsis models.

[Science Signaling] Investigators demonstrated that cytoplasmic, bioavailable zinc was essential for promoting IL-1β production in activated human monocytes and macrophages downstream of glycolysis induced by the kinase-containing multiprotein complex mTORC1.