myeloid cells

[Blood] Investigators suggested that serine-arginine rich splicing factor 3 (SRSF3) played a role in sorting cytoplasmic megakaryocyte RNAs into platelets and demonstratef how SRSF3-mediated RNA processing formed a central part of megakaryocyte gene regulation.

[Experimental and Molecular Medicine] Scientists identified and functionally validated a lncRNA using human atherosclerotic plaques. Human aortic samples were obtained from patients who underwent aortic surgery, and tissues were classified according to atherosclerotic plaques.

[Stem Cell Research & Therapy] Scientists summarize on the recent findings concerning the application of MSCs and their derivative exosome to support wound healing and skin regeneration, with special focus on last decade in vivo reports.

[Cell Reports Medicine] Scientists presented high-dimensional profiling of blood and respiratory samples in severe COVID-19 patients to examine the association between cell-linked molecular features and mortality outcomes.

[Gut] The authors used high-resolution endoscopy and colon tissue samples of active ulcerative colitis as well as experimental models of physical and chemical mucosal damage in mice deficient for peptidyl-arginine deiminase-4, gnotobiotic mice and controls.

[Nature Communications] Scientists generated a comprehensive prostate cancer transcriptome atlas that described the roadmap to tumor progression in a qualitative and quantitative manner. Using patient-derived xenograft models, they functionally validated their observations and add single-cell resolution.