myocardial infarction

[Genomics] The authors explored the mechanism of human umbilical cord MSCs-derived extracellular vesicles loaded with miR-223 on myocardial infarction.

[Seminars in Immunopathology] Innate immune cells contain the molecular circadian clock which drives rhythmic responses, from the magnitude of the inflammatory response to the numbers of circulating immune cells varying throughout the day.

[NPG Asia Materials] Scientists review variations in the myocardial microenvironment and the effects of functional hydrogel systems that are designed to support and mimic this microenvironment during cardiac repair following myocardial infarction.

[Cellular Signalling] Researchers found that PH domain leucine-rich repeat protein phosphatase1 (PHLPP1) deficiency enhanced Thr163 phosphorylation of Mcl-1, inhibited Mcl-1 degradation and maintained Mcl-1 protein expression level in myocardium and cardiomyocytes upon myocardial infarction or Dox treatment.

[Biophysical Journal] Scientists engineered ribonucleotide reductase overexpressing human-induced pluripotent stem cell-derived cardiomyocytes as a novel cell therapy strategy to improve contractility and regeneration in myocardial infarction.

[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.