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myocardial infarction

Long Non-Coding RNA McM3ap Antisense RNA 1 Silencing Upregulates microRNA-24-3p to Accelerate Proliferation and Migration of Vascular Endothelial Cells in Myocardial Infarction Rats by...

[Cell Cycle] The vascular endothelial cells (VECs) were isolated and treated severally, and then proliferation and migration of VECs were measured.

Cardiomyocyte IL-1R2 Protects Heart from Ischemia/Reperfusion Injury by Attenuating IL-17RA-Mediated Cardiomyocyte Apoptosis

[Cell Death & Disease] After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.

Mechanism of miR-378a-3p Enriched in M2 Macrophage-Derived Extracellular Vesicles in Cardiomyocyte Pyroptosis after MI

[Hypertension Research] An in vitro cell model was established, followed by a comprehensive evaluation of cell viability and pyroptosis. The binding relationships of miR-378a-3p and ELAVL1, HuR, and NLR family pyrin domain containing 3 were analyzed.

Therapeutic Potential of Colchicine in Cardiovascular Medicine: A Pharmacological Review

[Acta Pharmacologica Sinica] The authors summarize the current clinical trials with proven curative effect of colchicine in treating cardiovascular diseases.

An MMP-Degradable and Conductive Hydrogel to Stabilize HIF-1α for Recovering Cardiac Functions

[Theranostics] A conductive and injectable hydrogel crosslinked by matrix metalloproteinase (MMP)-sensitive peptides was rationally constructed to stabilize hypoxia-inducible factor-1α (HIF-1α) to recover heart functions after myocardial infarction.

Immune Cells in Cardiac Homeostasis and Disease: Emerging Insights from Novel Technologies

[European Heart Journal] The authors summarize novel findings on immune cell heterogeneity and functions in cardiac disease with a focus on myocardial infarction as a prototypic example.

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