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myocardial infarction

Loss of Exosomal LncRNA HCG15 Prevents Acute Myocardial Ischemic Injury through the NF-κB/p65 and p38 Pathways

[Cell Death & Disease] RNA sequencing was conducted to investigate the exosomal long non-coding RNA (lncRNA) transcriptome from myocardial infarction (MI) patients and identified 65 differentially expressed lncRNAs between the MI and control groups.

Cardiac Aorta-Derived Extracellular Matrix Scaffold Enhances Critical Mediators of Angiogenesis in Isoproterenol-Induced Myocardial Infarction Mice

[Journal of Materials Science-Materials in Medicine] The authors investigated whether cardiomyocytes culturing on cardiac aorta-derived extracellular matrix scaffold had advantageous effects on cardiomyocytes survival and angiogenesis biomarkers’ expression.

LncRNA TUG1 Aggravates Cardiomyocyte Apoptosis and Myocardial Ischemia/Reperfusion Injury

[Histology and Histopathology] Researchers reported that TUG1 expression was induced in mouse heart following myocardial ischemia/reperfusion injury as well as in cardiomyocytes subjected to simulated ischemia/reperfusion in vitro.

Development of Injectable Graphene Oxide/Laponite/Gelatin Hydrogel Containing Wharton’s Jelly Mesenchymal Stem Cells for Treatment of Oxidative Stress-Damaged Cardiomyocytes

[Colloids and Surfaces B-Biointerfaces] Injectable GO/laponite/gelatin (GO-LG) hydrogel was developed and characterized. The results of cell viability showed that the optimal concentration of GO flasks to treat cells was 100 μg/ml.

METTL3 Improves Cardiomyocyte Proliferation upon Myocardial Infarction via Upregulating miR-17-3p in a DGCR8-Dependent Manner

[Cell Death Discovery] Due to the role of methyltransferase-like 3 (METTL3) in the physiological proliferation of cardiomyocytes, researchers aimed to determine whether METTL3 could also promote cardiomyocyte proliferation under pathological conditions and to elucidate the underlying mechanism.

Conquering the Cytokine Storm in COVID-19-Induced ARDS Using Placenta-Derived Decidua Stromal Cells

[Journal of Cellular and Molecular Medicine] Researchers conducted a safety and efficacy study that included ten patients with a median age of 50 years with COVID-19-induced acute respiratory distress syndrome (ARDS).

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