myocardium

[Scientific Reports] Researchers proposed that cardiomyocyte-driven paracrine signaling, which likely involves Notch1, directs subsequent trans-differentiation of endo- and epicardial cells.

[Journal of Materials Science-Materials in Medicine] The authors investigated whether cardiomyocytes culturing on cardiac aorta-derived extracellular matrix scaffold had advantageous effects on cardiomyocytes survival and angiogenesis biomarkers’ expression.

[Longeveron, Inc.] Longeveron, Inc. announced the activation of two new clinical sites for the currently enrolling ELPIS II Trial, evaluating Lomecel-B injection into the myocardium of infants with Hypoplastic Left Heart Syndrome, a rare and life-threatening congenital heart defect.

[Colloids and Surfaces B-Biointerfaces] Injectable GO/laponite/gelatin (GO-LG) hydrogel was developed and characterized. The results of cell viability showed that the optimal concentration of GO flasks to treat cells was 100 μg/ml.

[Science Advances] Scientists demonstrated that suppression of FGFR1 and OSMR by miR-1/133a was instrumental to prevent cardiomyocyte dedifferentiation and cell cycle entry in the adult heart.

[JCI Insight] Scientists demonstrated that potentially novel conditional cardiomyocyte–specific miR-150 knock out in mice worsened maladaptive cardiac remodeling after myocardial infarction.